Eastern region of Indonesia has caught the world’s attention for its mega biodiversity. In the last five decades, the modernist food and agricultural practices has become one of the contributing factors that triggers the environmental changes in this region. The productivist paradigm in Indonesian food policies to feed 260 million people targets the self-sufficiency of rice, sago, corn, soybean, and meat production, including the infrastructure development such as dams, irrigation channels building, and the expansion of paddy and sago fields in the Eastern Indonesia. The unintended outcomes of these efforts are the marginalization of the local food system and dispossession of the local communities from their land and food culture. As a consequence, the human-environmental relationship has changed dramatically posing calamitous disaster and slowly disappearing foodways through local wisdom in everyday life of the local community. It also brings health issues due to the excessive use of chemical agricultural inputs in production, and the increase of degenerative disease and obesity due the unhealthy practices in the consumption level.
Beyond these circumstances, problematic issues mentioned above are the challenge of the current and future sustainable development in the region. Therefore, to tackle problems, the need for robust strategies of sustainable innovation in Agricultural sustainability to Ensure Food safety and security in achieving Sustainable development goals 2030 is put forward.